Overview of Clenpiq
CLENPIQ is a prescription oral solution containing sodium picosulfate, magnesium oxide, and citric acid, designed for colon cleansing before colonoscopies in adults and children aged 9+. It is contraindicated in severe renal impairment, GI obstruction, or hypersensitivity to its ingredients, emphasizing the importance of proper hydration and adherence to instructions.
1.1 What is Clenpiq?
CLENPIQ is a prescription oral solution containing sodium picosulfate, magnesium oxide, and anhydrous citric acid. It is designed for colon cleansing in adults and children aged 9 and older undergoing colonoscopies. The solution works to stimulate bowel movements and prepare the colon for a clear viewing during the procedure, ensuring effective cleansing when proper instructions are followed.
1.2 Purpose of Clenpiq in Colonoscopy Preparation
CLENPIQ is specifically designed to cleanse the colon for a clear view during colonoscopy. Its purpose is to stimulate bowel movements, removing stool and debris, which enhances visibility for accurate diagnosis. As part of a bowel prep routine, it ensures the colon is adequately prepared, making the procedure more effective and reliable for detecting abnormalities.
Key Steps for Using Clenpiq
Drink the first bottle of Clenpiq, follow hydration instructions, and complete the second dose as directed to ensure proper colon cleansing for a safe and effective procedure.
2.1 Drinking the First Bottle
Drink the entire first bottle of Clenpiq in the evening before the procedure, typically between 5:00 PM and 9:00 PM. Swallow the solution quickly without diluting it. Avoid refrigerating the bottle beforehand to ensure the solution is palatable. After consumption, follow up with five 8-ounce glasses of clear liquids over the next three hours to stay hydrated and aid the cleansing process effectively.
2.2 Hydration Instructions
After drinking the first bottle of Clenpiq, consume at least five 8-ounce glasses of clear liquids over the next three hours. Clear liquids include water, clear broth, or electrolyte solutions. Avoid red or purple liquids to prevent interference with colonoscopy results. Stay hydrated before, during, and after the prep to ensure effective cleansing and minimize discomfort or dehydration risks.
2.3 Timing of the Second Dose
The second dose of Clenpiq should be taken 6 hours before your scheduled colonoscopy time. Drink the second bottle in the morning, followed by at least five 8-ounce glasses of clear liquids over the next two hours. Complete all liquid intake 4 hours prior to the procedure to ensure proper bowel cleansing and avoid solid foods after the second dose.
Important Safety Information
CLENPIQ has specific contraindications and requires proper hydration to minimize risks. Patients must follow their doctor’s advice and review all precautions to avoid complications during preparation.
3.1 Contraindications
CLENPIQ is contraindicated in patients with severe renal impairment (creatinine clearance <30 mL/minute), gastrointestinal obstruction, ileus, or hypersensitivity to its components. It should not be used in cases of bowel perforation, toxic colitis, or megacolon. Additionally, individuals with gastric retention or known allergies to sodium picosulfate, magnesium oxide, or citric acid must avoid using CLENPIQ. Consult your healthcare provider for alternative options if any of these conditions apply.
3.2 Warnings and Precautions
CLENPIQ may cause dehydration or electrolyte imbalances, especially in vulnerable populations. Monitor for symptoms like dizziness or fainting. Patients with kidney issues should use caution. Administer with caution in pediatric patients aged 9 and older, as safety and efficacy have been established in this group. Always follow hydration guidelines to minimize risks associated with bowel preparation.
Hydration Guidelines
Hydration is critical during Clenpiq prep. Drink clear liquids before, during, and after taking Clenpiq to prevent dehydration. Aim for at least five 8-ounce glasses after each dose.
4.1 Why Hydration is Crucial
Hydration is essential for Clenpiq to work effectively. It helps prevent dehydration, ensures the laxative works properly, and makes the colonoscopy procedure safer. Proper fluid intake softens stool and clears the colon, improving visibility during the exam. Inadequate hydration can lead to side effects like dizziness or electrolyte imbalances, so drinking as instructed is vital for both safety and success.
4.2 Recommended Fluid Intake
After drinking Clenpiq, consume at least five 8-ounce glasses of clear liquids over the next three hours. Continue hydrating as instructed by your doctor. Clear liquids like water, clear broth, or electrolyte solutions are recommended to prevent dehydration and ensure the medication works effectively. Proper fluid intake helps maintain electrolyte balance and supports the cleansing process for a successful colonoscopy.
Dietary Restrictions
A clear liquid diet is required the day before and during the prep. Avoid solid foods, red liquids, and iron supplements. Only clear liquids like water, clear broth, or electrolyte solutions are permitted to ensure proper cleansing and prevent interference with the procedure.
5.1 Clear Liquid Diet
A clear liquid diet is essential the day before and during the prep. Allowed fluids include water, clear broth, electrolyte solutions, and black coffee or tea without milk. Avoid solid foods, red liquids, dairy, and iron supplements. This diet helps ensure the colon is cleansed effectively and prevents interference with the procedure. Stick strictly to clear liquids to achieve optimal preparation with Clenpiq.
5.2 Foods to Avoid
During Clenpiq prep, avoid solid foods, red or purple liquids, dairy products, and iron supplements. These can interfere with colon cleansing or obscure visibility. Stop consuming high-fiber foods, nuts, seeds, and anything not clear. Adhere strictly to the clear liquid diet to ensure effective preparation and avoid complications. Proper dietary restriction is crucial for a successful colonoscopy procedure and accurate results.
Detailed Timing Schedule
Take the first Clenpiq dose between 5:00 PM and 9:00 PM the evening before the procedure. The second dose is taken 6 hours before the colonoscopy, with clear liquids allowed until 4 hours prior.
6.1 Evening Before the Procedure
Drink the first bottle of Clenpiq between 5:00 PM and 9:00 PM. Do not refrigerate the bottle. Consume the solution as directed without dilution. After drinking, hydrate with at least five 8-ounce glasses of clear liquids over the next three hours. Avoid solid foods and follow the clear liquid diet. Ensure all liquids are consumed by 4 hours before the procedure to ensure proper preparation.
6.2 Morning of the Procedure
On the morning of the procedure, take the second bottle of Clenpiq 6 hours before your scheduled colonoscopy time. Drink the solution as directed, followed by clear liquids to stay hydrated. Complete all liquid intake 4 hours prior to the procedure to ensure proper bowel cleansing. Avoid solid foods and adhere strictly to the clear liquid diet to maintain effectiveness and safety.
Medication Considerations
Medication considerations involve consulting your provider about blood thinners and diabetes medications. Adjustments may be necessary to ensure safety during the colonoscopy preparation process with Clenpiq.
7.1 Blood Thinners
Patients on blood thinners, such as Aggrenox, Brilinta, Coumadin, Eliquis, Plavix, Pradaxa, Warfarin, or Xarelto, should contact their provider for specific instructions. Guidance may vary to ensure safe colonoscopy preparation while managing bleeding risks. Always follow your provider’s recommendations regarding medication adjustments during the Clenpiq prep to minimize complications and achieve optimal results.
7.2 Diabetes Medications
Patient with diabetes should follow specific instructions from their healthcare provider regarding medication adjustments during Clenpiq preparation. Blood sugar monitoring is crucial, and medications may need to be temporarily adjusted to prevent hypoglycemia or hyperglycemia. Clear liquid intake should align with dietary restrictions, and hydration must be maintained as directed to ensure safety and effectiveness of the bowel prep.
Special Populations
CLENPIQ is approved for pediatric patients aged 9 and older. Patients with severe renal impairment (creatinine clearance <30 mL/min) should avoid its use due to increased risks.
8.1 Pediatric Use
CLENPIQ is approved for children aged 9 and older for colon cleansing prior to colonoscopy. Dosage instructions remain the same as for adults, with one bottle taken in the evening and a second dose on the morning of the procedure. Adult supervision is recommended to ensure proper administration and adherence to the preparation instructions for safe and effective use in pediatric patients.
8.2 Renal Impairment
CLENPIQ is contraindicated in patients with severe renal impairment (creatinine clearance less than 30 mL/minute). Use in such patients is not recommended due to the increased risk of complications. Patients with renal impairment should consult their healthcare provider for alternative bowel preparation options. Proper medical guidance is essential to ensure safe and effective preparation for colonoscopy.
Storage Instructions
Store CLENPIQ bottles at room temperature (15°C to 30°C) in a dry place. Do not refrigerate or freeze. Keep the bottles tightly sealed and out of reach of children to maintain effectiveness and safety.
Avoid exposing the solution to direct sunlight or moisture; Proper storage ensures the medication remains stable and effective for use during the colonoscopy preparation process.
9.1 Proper Storage Conditions
Store CLENPIQ bottles at room temperature (15°C to 30°C) in a dry, secure location. Avoid refrigeration, freezing, or exposure to direct sunlight. Keep bottles tightly sealed to prevent moisture exposure. Ensure the solution is protected from direct sunlight and humidity to maintain its potency and effectiveness. Do not store in areas accessible to children or pets. Proper storage conditions are essential for the stability and safety of the medication.
9.2 What to Avoid
Do not refrigerate CLENPIQ bottles, as this may alter the solution’s effectiveness. Avoid diluting the solution or mixing it with other liquids. Do not leave bottles open or exposed to air for extended periods. Never reuse a bottle once opened; Ensure the solution is consumed within the instructed timeframe to maintain its potency and safety. Proper handling is crucial for effective bowel preparation and patient safety.
Common Side Effects
CLENPIQ may cause gastrointestinal symptoms such as nausea, bloating, or stomach pain. Other possible reactions include headache or dizziness. These effects are usually mild and temporary.
10.1 Gastrointestinal Symptoms
Gastrointestinal symptoms such as nausea, bloating, or stomach pain may occur with CLENPIQ. These side effects are generally mild and temporary, resolving on their own. Proper hydration can help alleviate discomfort. If symptoms persist or worsen, consult your healthcare provider for further guidance.
10.2 Other Possible Reactions
Beyond gastrointestinal symptoms, CLENPIQ may cause dizziness, headaches, or electrolyte imbalances. Rarely, allergic reactions like rash or swelling can occur. If you experience severe or unusual side effects, such as difficulty breathing, seek medical attention immediately. Proper hydration and adherence to instructions can help minimize these risks. Always consult your healthcare provider if concerns arise.
Preparing the Night Before
Gather all supplies, including CLENPIQ bottles and clear liquids. Drink the first bottle as instructed, followed by five 8-ounce glasses of clear liquids. Avoid solid foods and ensure proper hydration to prepare for the procedure effectively.
11.1 Gathering Supplies
To ensure a smooth preparation process, gather all necessary supplies the night before. This includes the CLENPIQ kit, clear liquids (e.g., water, clear broth), a list of medications, and a timer. Keep the CLENPIQ bottles at room temperature and avoid refrigeration. Have a glass or cup ready for drinking. Prepare a list of clear liquids to consume as instructed. Hydration is crucial, so plan accordingly and stay organized to follow the preparation schedule effectively.
11.2 Final Preparations
Before bed, ensure all supplies are ready. Drink the first bottle of CLENPIQ as instructed, followed by five 8-ounce glasses of clear liquids. Avoid solid foods and stick to the clear liquid diet; Prepare any necessary medications and confirm the colonoscopy time. Double-check the instructions and plan for transportation. Rest well to ensure you’re ready for the procedure the next day. Proper preparation ensures a smooth experience.
Emergency Situations
- Severe reactions: Seek immediate medical help if you experience difficulty breathing, chest pain, or severe abdominal distress.
- Incomplete prep: If bowel prep is inadequate, contact your healthcare provider for further instructions.
12.1 Severe Reactions
In rare cases, severe allergic reactions or acute symptoms like difficulty breathing, chest pain, or severe abdominal distress may occur. If these symptoms arise, seek emergency medical care immediately. Do not delay seeking help, as severe reactions can be life-threatening. Inform healthcare providers of your Clenpiq use and any known allergies to ensure prompt and appropriate treatment.
12.2 Incomplete Bowel Prep
If bowel prep is incomplete, your colon may not be adequately cleansed, reducing the effectiveness of the colonoscopy. Contact your doctor immediately. They may recommend repeating the prep or adjusting your schedule. Ensure all instructions are followed precisely to avoid this issue, as incomplete prep can delay or require repeating the procedure, affecting diagnostic accuracy and patient care.